Copa Airlines — the regional workhorse

Copa's Panama City hub is the single most useful connection point for travelers reaching Cuba from anywhere in South America. Same-airline connections to HAV, VRA, HOG, and SCU make it the path of least resistance for travelers from Bogotá, Lima, Santiago, Buenos Aires, and São Paulo.

Mexico — Aeroméxico and Viva Aerobus

Aeroméxico runs daily Mexico City → Havana. Viva Aerobus offers low-cost service from MEX and CUN. For travelers from the U.S. who want to avoid the OFAC ticket-counter process, connecting via Cancún on Viva Aerobus is a popular workaround — but the OFAC requirement still applies.

Dominican Republic — W2Fly

W2Fly runs scheduled service from Punta Cana and Santo Domingo to Havana. Useful for travelers combining a Cuba trip with a stay on Hispaniola.

Carrier status

6 of 6 airlines
Routes
Copa Airlines
Main Latin American hub via Panama.
OperatingLatin AmericaPTY → HAV / VRA / HOG / SCU21
W2Fly
Dominican Republic operator.
OperatingLatin AmericaPUJ/SDQ → HAV4
Aeroméxico
Daily Mexico City service.
OperatingLatin AmericaMEX → HAV7
Viva Aerobus
Low-cost from Mexico.
OperatingLatin AmericaMEX/CUN → HAV5
LATAM Perú
SuspendedLatin AmericaLima route ended 2025
Magnicharters
SuspendedLatin AmericaMexico charter paused